NCLEX Question for classes of antineoplastic agents is cell--cycle-specific

NCLEX Review Question

Which of the following classes of antineoplastic agents is cell--cycle-specific?

a.Antimetabolites (5-FU)
b.Antitumor antibiotics (bleomycin)
c.Alkylating agents (cisplatin)
d.Nitrosureas (carmustine)

Correct Answer: A
Antimetabolites (5-FU)
Rationale: Antimetabolites are cell--cycle-specific (S phase).

Antitumor antibiotics (bleomycin)
Rationale: Antitumor antibiotics are cell-cycle nonspecific.

Alkylating agents (cisplatin)
Rationale: Alkylating agents are cell-cycle nonspecific.

Nitrosureas (carmustine)
Rationale: Nitrosureas are cell-cycle nonspecific.

Posted in: MSN NCLEX